Short Notes
Allergy
1.0 Core Terminology
- Allergy: Hypersensitivity of the immune system to a harmless substance.
- Allergen: The substance causing the reaction (e.g., Pollen, Dust).
- Antibody (IgE): Proteins produced by the body to "fight" the allergen.
- Histamine: The chemical released that causes swelling, itching, and redness.
2.0 Entry Routes
| Route | Examples |
|---|---|
| Inhalation | Pollen, Dust, Fur, Mold. |
| Ingestion | Milk, Eggs, Peanuts, Seafood. |
| Contact | Latex, Cosmetics, Nickel. |
| Injection | Bee stings, Penicillin. |
3.0 Quick Mechanism
Allergen → IgE Antibody → Mast Cells → Histamine Release
💡 Revision Tip: Remember that histamine is the main "villain" that causes symptoms, which is why we take anti-histamines to stop them!
4.0 Identifying Symptoms
| System | Common Symptoms |
|---|---|
| Respiratory | Sneezing, Running nose, Hay fever, Asthma. |
| Skin | Itching, Redness, Hives (Urticaria), Eczema. |
| Digestive | Vomiting, Stomach cramps, Diarrhea. |
5.0 How to Test?
- Skin Prick Test: Placing allergen drops on skin and pricking to check for red bumps.
- Blood Test: Checking for elevated levels of IgE antibodies.
- Elimination Diet: Stopping specific foods to see if the reaction stops.
6.0 Precautions & Emergencies
- Avoid known triggers (pollen, specific foods, pets).
- Carry an EpiPen (Epinephrine) for severe reactions.
- Wear masks in high-pollen areas.
- Read food labels for hidden allergens.
⚠️ Exam Note: Anaphylaxis is the most severe form of allergy. It causes a sudden drop in blood pressure and must be treated with Adrenaline immediately.
REVISION COMPLETE
Allergy: Full Short Notes finished.