⚡ Quick Revision: Endocrine System Essentials
- ✔ Hormones are chemical messengers secreted directly into the blood by ductless (endocrine) glands.
- ✔ They act on target organs or cells located away from the gland.
- ✔ Hormones are required in minute quantities; both hyper-secretion and hypo-secretion cause disorders.
Exocrine Glands: Glands that pour their secretions through ducts (e.g., salivary, sweat glands).
Nervous vs Hormonal control. Nervous is electrical and fast; Hormonal is chemical and generally slower but long-lasting.
⚡ Quick Revision: The Pituitary & Thyroid Glands
Master Gland: The Pituitary gland, so called because it controls the secretions of many other endocrine glands.
- ✔ Growth Hormone (GH): Essential for growth; deficiency causes Dwarfism, excess causes Gigantism.
- ✔ Tropic Hormones: TSH (stimulates Thyroid) and ACTH (stimulates Adrenal Cortex).
- ✔ Vasopressin (ADH): Regulates water reabsorption in the kidneys (deficiency leads to Diabetes Insipidus).
| Thyroid Hormone | Condition | Main Symptoms |
|---|---|---|
| Thyroxine (Hypo) | Simple Goitre / Myxoedema | Swelling in neck / Sluggishness |
| Thyroxine (Hyper) | Exophthalmic Goitre | Protruding eyes / Increased BMR |
Cretinism with Dwarfism. Cretinism is mental/physical retardation due to low thyroxine in infants; Dwarfism is physical smallness due to low GH.
⚡ Quick Revision: Pancreas & Adrenal Glands
Heterocrine Gland: A gland that performs both exocrine (enzymes) and endocrine (hormones) functions, such as the Pancreas.
- ✔ Insulin (Beta cells): Lowers blood glucose by converting glucose to glycogen in the liver.
- ✔ Glucagon (Alpha cells): Raises blood glucose by converting stored glycogen back into glucose.
- ✔ Diabetes Mellitus: Caused by insulin deficiency; characterized by "sugar in urine" (Glycosuria).
- ✔ Adrenaline (Medulla): The "Fight or Flight" hormone; increases heart rate and blood flow to muscles.
- ✔ Cortoids (Cortex): Regulate mineral metabolism and glucose levels.
- ✔ Disorders: Hyposecretion of cortical hormones causes Addison's Disease.
Diabetes Mellitus with Diabetes Insipidus. Mellitus involves Insulin/Sugar; Insipidus involves ADH/Water loss.
⚡ Quick Revision: Feedback Mechanism & Summary
Negative Feedback Mechanism: The body timing and amount of hormone release are controlled by this system. When the level of a substance (like glucose) rises, it triggers the gland to secrete a hormone (insulin) to bring it back to normal. Once normal, the secretion stops.
- ✔ Pituitary: GH, TSH, ADH (The Master).
- ✔ Thyroid: Thyroxine (Metabolism control).
- ✔ Pancreas: Insulin/Glucagon (Sugar balance).
- ✔ Adrenals: Adrenaline (Stress/Emergency).
Logic-Based Questions: Expect questions like "Why is the pancreas called a dual gland?" or "Why does a person's heart rate increase when frightened?" Answer with specific hormone names and their functions.